2022

Pedersen, C. B., Dam, S. H., Barnkob, M. B., Leipold, M. D., Purroy, N., Rassenti, L. Z., Kipps, T. J., Nguyen, J., Lederer, J. A., Gohil, S. H., Wu, C. J., Olsen, L. R. (2022). cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies. Nature Communications, 13, 1698. doi:10.1038/s41467-022-29383-5

Purroy Zuriguel, N., Tong, Y. E., Lemvigh, C. K., Cieri, N., Li, S., Parry, E. M., Zhang, W., Rassenti, L. Z., Kipps, T. J., Slager, S. L., Kay, N. E., Lesnick, C., Shanafelt, T. D., Ghia, P., Scarfò, L., Livak, K. J., Kharchenko, P., Neuberg, D., Olsen, L. R., Fan, J., Gohil, S. H., & Wu, C. J. (2022). Single cell analysis reveals immune dysfunction from the earliest stages of CLL that can be reversed by ibrutinib. Blood. doi:10.1182/blood.2021013926



2021

Gabrielaite, M., Torp, M. H., Rasmussen, M. S., Andreu-Sánchez, S., Vieira, F. G., Pedersen, C. B., Kinalis, S., Madsen, M. B., Kodama, M., Demircan, G. S., Simonyan, A., Yde, C. W., Olsen, L. R., Marvig, R. L., Østrup, O., Rossing, M., Nielsen, F. C., Winther, O., & Bagger, F. O. (2021). A Comparison of Tools for Copy-Number Variation Detection in Germline Whole Exome and Whole Genome Sequencing Data. Cancers, 13, 6283. doi:10.3390/cancers13246283

Barnkob, M. B., Benso, A., Politano, G., Olsen L. R. (2021). Spectracular: minimizing spectral overlap in multicolor flow cytometry experiments. bioRxiv. doi:10.1101/2021.03.17.435861

Rossing, M., Pedersen, C. B., Tvedskov, T., Vejborg, I., Talman, M. L., Olsen, L. R., Kroman, N., Nielsen, F. C., Jensen, M. B., & Ejlertsen, B. (2021). Clinical implications of intrinsic molecular subtypes of breast cancer for sentinel node status. Scientific Reports, 11(1), [2259]. doi:10.1038/s41598-021-81538-4

Kretzmer, H., Biran, A., Purroy, N., Lemvigh, C. K., Clement, K., Gruber, M., Gu, H., Rassenti, L., Mohammad, A. W., Lesnick, C., Slager, S. L., Braggio, E., Shanafelt, T. D., Kay, N. E., Fernandes, S., Brown, J. R., Wang, L., Li, S., Livak, K. J., Neuberg, D. S., Klages, S., Timmermann, B., Kipps, T. J., Campo, E., Gnirke, A., Wu, C. J., & Meissner, A. (2021). Preneoplastic alterations define CLL DNA methylome and persist through disease progression and therapy. Blood cancer discovery, 2(1), 54. doi:10.1158/2643-3230.BCD-19-0058

Braun, D. A., Street, K., Burke, K. P., Cookmeyer, D. L., Denize, T., Pedersen, C. B., Gohil, S. H., Schindler, N,, Pomerance, L., Hirsch, L., Bakouny, Z., Hou, Y., Forman, J., Huang, T., Li, S., Cui, A., Keskin, D. B., Steinharter, J., Bouchard, G., Sun, M., Pimenta, E. M., Xu, W., Mahoney, K. M., McGregor, B. A., Hirsch, M. S., Chang, S. L., Livak, K. J., McDermott, D. F., Shukla, S. A., Olsen, L. R., Signoretti, S., Sharpe, A. H., Irizarry, R. A., Choueiri, T. K., Wu, C. J. (2021). Progressive immune dysfunction with advancing disease stage in renal cell carcinoma. Cancer Cell. doi:10.1016/j.ccell.2021.02.013

Crump, N. T., Hadjinicolaou, A. V., Xia, M., Walsby-Tickle, J., Gileadi, U., Chen, J. L., Setshedi, M., Olsen, L. R., Lau, I. J., Godfrey, L. Quek, L., Yu, Z., Ballabio, E., Barnkob, M. B., Napolitani, G., Salio, M., Koohy, H., Kessler, B. M., Taylor, S., Vyas, P., McCullagh, J. S. O., Milne, T. A., Cerundolo, V. (2021). Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation. Cell reports, 35(6), p.109101. doi:10.1016/j.celrep.2021.109101

Choudry, F. A., Bagger, F. O., Macaulay, I. C., Farrow, S., Burden, F., Kempster, C., McKinney, H., Olsen, L. R., Huang, N., Downes, K., Voet, T., Uppal, R., Martin, J. F., Mathur, A., Ouwehand, W. H., Laurenti, E., Teichmann, S. A., & Frontini, M. (2021). Transcriptional characterization of human megakaryocyte polyploidization and lineage commitment. Journal of Thrombosis and Haemostasis. doi:10.1111/jth.15271

Hu, Z., Leet, D. E., Allesøe, R. L., Oliveira, G., Li, S., Luoma, A. M., Liu, J., Forman, J., Huang, T., Iorgulescu, J. B., Holden, R., Sarkizova, S., Gohil, S. H., Redd, R. A., Sun, J., Elagina, L., Giobbie-Hurder, A., Zhang, W., Peter, L., Ciantra, Z., Rodig, S., Olive, O., Shetty, K., Pyrdol, J., Uduman, M., Lee, P. C., Bachireddy, P., Buchbinder, E. I., Yoon, C. H., Neuberg, D., Pentelute, B. L., Hacohen, N., Livak, K. J., Shukla, S. A., Olsen, L. R., Barouch, D. H., Wucherpfennig, K. W, Fritsch, E. F., Keskin, D. B., Wu, C. J., & Ott, P. A. (2021). Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma. Nature Medicine, 1-11. doi:10.1038/s41591-020-01206-4



2020

Pedersen, C. B., & Olsen, L. R. (2020). Algorithmic Clustering Of Single‐Cell Cytometry Data—How Unsupervised Are These Analyses Really?. Cytometry Part A. doi:10.1002/cyto.a.23917

Kverneland, A. H., Pedersen, M., Westergaard, M. C. W., Nielsen, M., Borch, T. H., Olsen, L. R., Aasbjerg, G., Santegoets, S. J., van der Burg, S. H., Milne, K., Nelson, B. H., Met, Ö., Donia, M., & Svane, I. M. (2020). Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer. OncoTarget, 11(22), 2092-2105. doi:10.18632/oncotarget.27604

Westergaard, M. C. W., Milne, K., Pedersen, M., Hasselager, T., Olsen, L. R., Anglesio, M. S., Borch, T. H., Kennedy, M., Briggs, G., Ledoux, S., Kreuzinger, C., von der Decken, I., Donia, M., Castillo-Tong, D. C., Nelson, B. H., & Svane, I. M. (2020). Changes in the tumor immune microenvironment during disease progression in patients with ovarian cancer. Cancers, 12(12), [3828]. doi:10.3390/cancers12123828

Jørgensen, N. G., Klausen, U., Grauslund, J. H., Helleberg, C., Aagaard, T. G., Do, T. H., Ahmad, S. M., Olsen, L. R., Klausen, T. W., Breinholt, M. F., Hansen, M., Martinenaite, E., Met, Ö., Svane, I. M., Knudsen, L. M., & Andersen, M. H. (2020). Peptide Vaccination Against PD-L1 With IO103 a Novel Immune Modulatory Vaccine in Multiple Myeloma: A Phase I First-in-Human Trial. Frontiers in Immunology, 11, [595035]. doi:10.3389/fimmu.2020.595035



2019

Pedersen, C. B., & Olsen, L. R. (2019). Analysis of Mass Cytometry Data. In Mass Cytometry (pp. 267-279). Humana, New York, NY. doi:10.1007/978-1-4939-9454-0_17

Simon, C., Davidsen, K., Hansen, C., Seymour, E., Barnkob, M. B., & Olsen, L. R. (2019). BioReader: a text mining tool for performing classification of biomedical literature. BMC bioinformatics, 19(13), 57. doi:10.1186/s12859-019-2607-x

Jurtz, V. I., & Olsen, L. R. (2019). Computational methods for identification of T cell neoepitopes in tumors. In Cancer Bioinformatics (pp. 157-172). Humana Press, New York, NY. doi:10.1007/978-1-4939-8868-6_9

Olsen, L. R., Pedersen, C. B., Leipold, M. D., & Maecker, H. T. (2019). Getting the Most from Your High-Dimensional Cytometry Data. Immunity, 50(3), 535-536. doi:10.1016/j.immuni.2019.02.015

Li, S., Sun, J., Allesøe, R., Datta, K., Bao, Y., Oliveira, G., Forman, J., Jin, R., Olsen, L. R., Keskin, D. B., Shukla, S. A., Wu, C. J. & Livak, K. J. (2019). RNase H–dependent PCR-enabled T-cell receptor sequencing for highly specific and efficient targeted sequencing of T-cell receptor mRNA for single-cell and repertoire analysis. Nature protocols, 14(8), 2571-2594. doi:10.1038/s41596-019-0195-x

Olsen, L. R., Leipold, M. D., Pedersen, C. B., & Maecker, H. T. (2019). The anatomy of single cell mass cytometry data. Cytometry Part A, 95(2), 156-172. doi:10.1002/cyto.a.23621

Keskin, D. B., Anandappa, A. J., Sun, J., Tirosh, I., Mathewson, N. D., Li, S., Oliveira, G., Giobbie-Hurder, A., Felt, K., Gjini, E., Shukla, S. A., Hu, Z., Li, L., Le, P. M., Allesøe, R. L., Richman, A. R., Kowalczyk, M. S., Abdelrahman, S., Geduldig, J. E., Charbonneau, S., Pelton, K., Iorgulescu, J. B., Elagina, L., Zhang, W., Olive, O., McCluskey, C., Olsen, L. R., Stevens, J., Lane, W. J., Salazar, A. M., Daley, H., Wen, P .Y., Chiocca, E. A., Harden, M., Lennon, N. J., Gabriel, S., Getz, G., Lander, E. S., Regev, A., Ritz, J., Neuberg, D., Rodig, S. J., Ligon, K. L., Suvà, M. L., Wucherpfennig, K. W., Hacohen, N., Fritsch, E. F., Livak, K. J., Ott, P. A., Wu, C. J., Reardon, D. A. (2018). Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial. Nature, 565, 234-239. doi:10.1038/s41586-018-0792-9



2018

Napolitani, G., Kurupati, P., Teng, K. W. W., Gibani, M. M., Rei, M., Aulicino, A., Preciado-Llanes, L., Wong, M. T.; Becht, E., Howson, L., de Haas, P., Salio, M., Blohmke, C. J., Olsen, L. R., Pinto, D. M. S., Scifo, L., Jones, C., Dobinson, H. Campbell, D., Juel, H. B., Thomaides-Brears, H., Pickard, D., Bumann, D., Baker, S., Dougan, G., Simmons, A., Gordon, M. A., Newell, E. W., Pollard, A. J. & Cerundolo, Vincenzo (2018). Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses. Nature immunology, 19(7), 742-754. doi:10.1038/s41590-018-0133-z

Leipold, M. D., Obermoser, G., Fenwick, C., Kleinstuber, K., Rashidi, N., McNevin, J. P., Nau, A. N., Wagar, L. E., Rozot, V., Davis, M. M., DeRosa, S., Pantaleo, G., Scriba, T. J., Walker, B. D., Olsen, L. R. & Maecker, H. T. (2018). Comparison of CyTOF assays across sites: Results of a six-center pilot study. Journal of immunological methods, 453, 37-43. doi:10.1016/j.jim.2017.11.008

Pedersen, C. B., Nielsen, F. C., Rossing, M., & Olsen, L. R. (2018). Using microarray‐based subtyping methods for breast cancer in the era of high‐throughput RNA sequencing. Molecular oncology, 12(12), 2136-2146. doi:10.1002/1878-0261.12389

 

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